ABSTRACT
Since ancient times, the different parts of the bitter orange of Seville have been used as food or for healing. One of its current main applications is the obtaining of a wide range of flavonoids which, after years of research and development, have proved to provide numerous benefits for human health including action against COVID-19, which is under research at laboratory level. Among the flavonoids found in the bitter orange of Seville naringin can be highlighted, which is very beneficial for human health. On the other hand, essential oils have been extracted and used since ancient times, from ritual and religious uses to the current uses in cosmetics, perfumery, food and health. This chapter overviews the history of the bitter oranges of Seville, the essential oils and naringin (a bioflavonoid) that can be extracted from them and their potential applications. © 2021 by Nova Science Publishers, Inc.
ABSTRACT
Diosmin is the 7-rutinoside of 3 ', 5,7-trihydroxy-4'-methoxyflavone (7-O-rutinoside of diosmetin), and hespheridine is the 7-rutinoside of 3', 5,7-trihydroxy-4'-methoxyflavanone (7 -O-rutinoside hesperetin). Diosmin, is a gray-yellow or pale-yellow, hygroscopic powder, whereas hesperidine is in the form of light-yellow spherocrystals. Diosmin was isolated from fruits of the Citrus genus (C. sinensis, C. limonia), now it is obtained semi-synthetically from natural hesperidin. These flavonoids have, among others: antimicrobial, anti-inflammatory, anti-diabetic, anti-cancer, analgesic, antioxidant and possibly anti-virus activity, that cause COVID-19. The metabolism of diosmin takes place initially in the small intestine and involves demethoxylation and hydrolysis. In contrast, oxidation and conjugation take place in the liver. There is no presence of diosmin and diosmetin in the urine, which are mainly eliminated in the form of glucuronic acid conjugates. The dominant metabolite detected in urine samples is m-hydroxy-phenylpropionic acid, excreted in conjugated form. Diosmin may reduce the aggregation of Red Blood Cells, and thus it is able to reduce blood viscosity. The LD50 of the mixture of 90% diosmin and 10% hesperidin for rats is over 3 g/kg. The tests did not reveal any mutagenic effects or effects on reproductive functions. It also does not pose a significant threat during breast feeding, as it poorly passes into breast milk.
ABSTRACT
The entire world is entrapped by the contagious, lethal infectious Corona disease, brought about by the extreme intense respiratory syndrome corona virus 2 (SARS-CoV-2). The second wave of the Covid-19 pandemic has been more devastating than the first. The arrival of corona virus vaccines has meant good news for resuming a normal life. However, there are some cases that have been reported that the persons who have been vaccinated still test positive for COVID-19. Unlike the first wave (in 2020), the younger population is getting infection by a corona virus, especially those with comorbidities are at high risk. Evidence from the first wave of data on the mortality rate also suggests that people with weak immune systems, e.g., older people, children, and those with underlying medical issues, are more likely to be affected by Covid-19 disease. Therefore, by improving the human body's immunity, the risk of SARS-CoV-2 infections can be reduced. In this regard, medicinal plants can play an effective role in improving the body's immunity. Thus, in this paper, attempts are made to compile and discuss the use of various plants to boost immunity and also for the prevention of many respiratory diseases having symptoms and signs similar to Corona disease.
ABSTRACT
Background: Up to date drug-based treatments for COVID-19 have not been approved. The most effective way to face this public health problem is prevention with adequate nutrition, hygiene, and protection measures. Food has historically been used by people to improve their nutrition and complement the treatment or prevention of diseases. The various bioactive compounds of some foods are known, which in experimental studies demonstrated their antiviral and immunomodulatory action.
ABSTRACT
The 2nd International Conference on Energetics, Civil and Agricultural Engineering is an international event that has been successfully held in a hybrid mode (online and onsite) organized by the Tashkent Institute of Irrigation and Agricultural Mechanization Engineers (TIIAME), Tashkent, Uzbekistan. ICECAE is a privileged space to discuss current issues related to Energetics, Civil and Agricultural Engineering. This international event aims to explore emerging technologies and concepts in a collaborative way, bringing together scientists, researchers, engineers, students and professionals from different areas. ICECAE 2021 proceedings collected the latest research and results in the field of energetics, civil and agricultural engineering. All manuscripts published in the proceeding have been through rigorous review and process to meet the requirements of international publication standard. In the honorable and keynote speeches sessions, honorable speakers were each allocated 40 minutes and keynote speakers were each allocated 20-25 minutes to hold their speeches. We were honored to invite 3 honorable speakers (Professor Josep M. Guerrero, Professor Saifur Rahman, and Professor Mohammad Shahidehpour) and 10 distinguished experts as keynote speakers to present their insightful speeches. As honorable speakers, Professor Josep M. Guerrero (from Aalborg University – Denmark) talked about Space Microgrids – NanoSats, Lunar Bases and Closed Ecosystems, Professor Saifur Rahman (from Virginia Tech Advanced Research Institute - USA) delivered a speech on Global Electric Power Sector: Engaging with Environmental Issues, and Professor Mohammad Shahidehpour (from Illinois Institute of Technology - USA) held a speech on Blockchain for Transactive Energy Management in Renewable Energy Systems. As keynote speakers, Prof. Dr. Jan Wincenty Dobrowolski (AGH University of Science and Technology - Poland) shared his experiences related to his 50 years contribution to global cooperation on Sustainable Development 1971-2021 and innovative proposals for adaptation to climate change, COVID-19 and outer-space missions;Professor emeritus Dr. Davidas Belsare (from Bhopal University - India) made a speech about the effect of laser diode on oranges to other fruit crops like guava and papaya;Professor Justyna Kobylarczyk and Professor Michal Krupa (from Cracow University of Technology – Poland) held a speech on the topic of high quality of residential environment;Professor Jose Osvaldo B. Carioca (from Federal University of Ceara - Brazil) expressed his keynote address about synthesis of chitosan membranes to be used in dual system of dark fermentation and MEC-electrolyzers to produce high quality hydrogen;Professor Dominika Kusnierz-Krupa and Dr. Malgorzata Hryniewicz (from Cracow University of Technology -Poland) made their talk about a new functions in a historic buildings;Professor Alirza Mamedov (from Kyiv National University of Construction and Architecture - Ukraine) delivered his talk about historical city analysis;Professor Manoj Stephen Paul and Dr. Ritu Chaturvedi (from St. Johns College - India) made their speech on human health risk assessment associated with consumption of food containing heavy metals;Associate professor Pavel Navitski (from Oral Roberts University – USA) delivered his talk about drift control during field spraying;and Dr. Ulrich Berk (president of the German Association of Homatherapy - Germany) made his keynote speech about agnihotra and homa farming -tools for a sustainable development on planet Earth. List of ICECAE 2021 Committee are available in this pdf.